GM Technology
Modelling the ecological consequences of emerging genetic technologies
GM Technology explores the ecological implications of emerging genetic technologies designed to control mosquito-borne disease. Using mathematical, ecological, and data-driven modelling approaches, this research investigates how gene drives and biological control systems interact with mosquito ecology across scales.
Current projects focus on high-threshold gene drive systems intended for localised population modification, particularly in mosquitoes such as Aedes aegypti. Research examines how ecological processes such as density dependence, resource competition, and life-stage interactions shape the behaviour and effectiveness of gene drives, addressing major gaps in existing risk assessment frameworks.
Other work investigates the use of Wolbachia bacteria as a biological control agent for invasive European mosquito populations carrying diseases such as Dengue, Zika, and Chikungunya. Statistical and mathematical models are used to explore how Wolbachia affects mosquito fitness, pathogen transmission, and population dynamics.
These projects aim to improve understanding of how genetic and ecological processes interact, helping evaluate the safety, containment, and effectiveness of future vector-control technologies.
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Keywords
Gene drives; mosquito ecology; biological control; disease vectors; ecological modelling
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GM Technology
Modelling the ecological consequences of emerging genetic technologies
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